Anacardic Acids from Cashew Nuts Ameliorate Lung Damage Induced by Exposure to Diesel Exhaust Particles in Mice

Figure 2

Glutathione reductase (a), glutathione peroxidase (b), glutathione S-transferase (c), and catalase (d) activities in lungs. Values represent means ± SEM. Ctrl: control; animals received an intranasal instillation of 10 𝜇L saline solution and were treated orally with 100 𝜇L of cashew nut oil (CNO). DEP: diesel exhaust particles; intranasal instillation of 50 𝜇g DEP/10 𝜇L of saline and treated orally with 100 𝜇L of CNO. DA50: intranasal instillation of 50 𝜇g DEP/10 𝜇L of saline and treated orally with 50 mg/kg of AAs. DA150: intranasal instillation of 50 𝜇g DEP/10 𝜇L of saline and treated orally with 150 mg/kg of AAs. DA250: intranasal instillation of 50 𝜇g DEP/10 𝜇L of saline and treated orally with 250 mg/kg of AAs. ^#𝑃<0.05 relative to Ctrl. ^∗𝑃<0.05 relative to DEP. ^##𝑃<0.001 relative to Ctrl. ^∗∗𝑃<0.001 relative to DEP.

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