Triterpenoid Saponins Isolated from Platycodon grandiflorum Inhibit Hepatitis C Virus Replication

Table 2

Inhibitory effects of triterpenoid saponins on HCV replication in HCV replicon cells and in HCVcc-infected cells.

Compounds	Inhibition of HCV RNA replication (EC50, 𝜇g/mL)		Cytotoxicity (CC50, 𝜇g/mL)
	CON1 (genotype 1b)	JHF-1 (genotype 2a)
PG-extract	35		>100
PGSM	0.78	8	25
Platycodin D	0.35	3	25
Platycodin D2	1.05	12	25
Platycodin D3	2.33	27	100
Deapioplatycodin D	1.2	7	25
Deapioplatycodin D2	0.89	8	100
Platyconic acid A	2.45	22	100