Attenuation of CCl₄-Induced Oxidative Stress and Hepatonephrotoxicity by Saudi Sidr Honey in Rats

Table 2

Effect of honey on CCl₄-induced lipid profile changes in rats.

Treatment group (𝑛=6)	Cholesterol (mg/dL)	Triglycerides (mg/dL)	HDL (mg/dL)	LDL (mg/dL)	VLDL (mg/dL)
Normal control	13.79±1.22	91.34±4.57	52.56±6.14	68.98±6.14	105.33±3.81
CCl4 only (1.25 mL/kg)	43.61±1.58^***a	237.63±10.61^***a	23.47±1.09^***a	218.05±7.94^***a	281.33±11.01^***a
Honey (0.5 g/kg) + CCl4	34.35±1.63^**b	172.29±8.93^***b	31.28±1.12^**b	171.29±8.19^**b	206.66±9.77^***b
Honey (1.0 g/kg) + CCl4	20.00±1.17^***b	170.50±6.46^***b	44.38±1.97^***b	100.00±5.87^***b	190.66±6.97^***b
Silymarin (10 mg/kg) + CCl4	38.79±0.80^*b	198.43±9.82^*b	29.27±1.55^*b	199.98±4.02^*b	237.33±9.16^*b

All values represent mean ± SEM. *𝑃<0.05; **𝑃<0.01; ***𝑃<0.001; ANOVA, followed by Dunnett’s multiple comparison test.
^aAs compared with normal group, ^bAs compared with CCl₄ only group.