Evidence-Based Complementary and Alternative Medicine

Research Article

Melinjo (Gnetum gnemon L.) Seed Extract Decreases Serum Uric Acid Levels in Nonobese Japanese Males: A Randomized Controlled Study

Table 1

The effects of melinjo seed extract administration for 8 weeks in adult men.
 Week 0Week 4Week 8
 Melinjo ( )Placebo ( )Melinjo ( )Placebo ( )Melinjo ( )Placebo ( )
  Means ± SDMeans ± SDMeans ± SDMeans ± SDMeans ± SDMeans ± SD
Body weight (kg) 0.96
Fat percentage (%) 0.946
BMI (kg/m2) 0.965
Systolic blood pressure (mmHg) 0.708
Diastolic blood pressure (mmHg) 0.756
Pulse (bpm) 0.711
FMD (%) 0.233
baPWV (right) (cm/s) 0.27
baPWV (left) (cm/s) 0.287
Ankle-brachial index (right) 0.549
Ankle-brachial index (left) 0.41
Total protein (g/dL) 0.156
Albumin (g/dL) 0.771
Total bilirubin (mg/dL) 0.956
Aspartate aminotransferase (U/L) 0.074
Alanine aminotransferase (U/L) 0.096
Gamma-glutamyl transpeptidase (U/L) 0.289
Total cholesterol (mg/dL) 0.654
HDL cholesterol (mg/dL) 0.111
LDL cholesterol (mg/dL) 0.871
Triglycerides (mg/dL) 0.381
Arteriosclerotic index 0.346
Uric acid (mg/dL) 0.009*
Blood urea nitrogen (mg/dL) 0.992
Creatinine (mg/dL) 0.283
Sodium (mEq/L) 0.629
Potassium (mEq/L) 0.284
Chlorine (mEq/L) 0.74
Blood sugar (mg/dL) 0.837
Hemoglobin A1c (%) 0.58
Albumin globulin ratio 0.666
White blood cell (×104/μL) 0.894
Red blood cell (×104/μL) 0.185
Hemoglobin (g/dL) 0.161
Hematocrit (%) 0.15
Mean cell volume (fL) 0.862
Mean cell hemoglobin (pg) 0.2
Mean cell hemoglobin concentration (g/dL) 0.756
Platelets (×104/μL) 0.685
Fasting IRI (μU/mL) 0.407
HOMA-IR 0.404
NT-proBNP (pg/mL) 0.505
RLP cholesterol (mg/dL) 0.242
Total homocysteine (mg/dL) 0.399
d-ROMs test (U.CARR) 0.781
BAP test (μmol/L) 0.633
Urine PH 0.008*
Urine specific gravity 0.689
BAP: biological antioxidant potential; d-ROMS: reactive oxygen metabolites-derived compounds; LDL: low-density lipoprotein; NT-proBNP: amino-terminal probrain natriuretic peptide; RLP: remnant-like particles. Values are given as means ± SD. for interaction. .