Review Article
The Anti-Inflammatory Effects of Acupuncture and Their Relevance to Allergic Rhinitis: A Narrative Review and Proposed Model
| Role of SP and CGRP in allergic rhinitis: | (i) promote vasodilation and plasma extravasation in nasal epithelium (nasal congestion) | (ii) SP and CGRP act synergistically and potentiate each other in mast cell degranulation | (early-phase allergic response) and plasma extravasation (nasal congestion) | (iii) activate monocytes to release pro-inflammatory cytokines (early-phase allergic response) | (iv) increase eosinophil accumulation in nasal mucosa during repeated allergen exposure | (v) SP promotes production and release of NGF |
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