Electroacupuncture at Zusanli (ST36) Prevents Intestinal Barrier and Remote Organ Dysfunction following Gut Ischemia through Activating the Cholinergic Anti-Inflammatory-Dependent Mechanism
Figure 4
Intestinal ZO-1 immunofluorescence at 60 min after reperfusion. Animals in the IR group showed a low fluorescent intensity at the cell periphery after iI/R injury (a), and EA ST36 showed preservation of the robust structure of ZO-1 staining (b), VNS and PNU282987 similarly prevented the degeneration of ZO-1 (c and d), abdominal vagotomy or α-BGT administration performed before EA ST36 eliminates the protective effect (e and f). All images are taken at ×400 magnification with black bar = 5 μm ( animals per group, size bar = 2 μm).
