A Network-Based Systematic Study for the Mechanism of the Treatment of Zhengs Related to Cough Variant Asthma

Figure 5

Herb-ingredient network. In this network, circular nodes are ingredients, square nodes are herbs, and an edge represents that an ingredient is a composition of an herb. Different colors stand for different target clusters. The shades of the colors represent the relation intensity of an ingredient to a disease-related target cluster. To be more specific, if the number of targets in Cluster 4 is larger than targets in Cluster 5, the ingredient is assigned purple, and the ingredient is assigned blue if the number of targets in Cluster 5 is larger. The shade of the color is proportional to the absolute value (ranging from 1 to 7) of the difference of the number of targets in Cluster 4 and Cluster 5. The only ingredient, with an absolute value of zero, was colored as bluish violet. Ingredients with targets which are not in disease-related target clusters are yellow, and those ones without any targets are not shown in this network. As the ingredients were hardly collected, they are not the overall compositions, but they can elucidate the problem in some degree.