Antidiabetic and Hypolipidemic Activities of Curculigo latifolia Fruit:Root Extract in High Fat Fed Diet and Low Dose STZ Induced Diabetic Rats

Table 6

Effect of C. latifolia extracts on ALT, GGT, urea, and creatinine levels in HFD and low dose STZ induced diabetic rats.

Group	ALT (U/L)		GGT (U/L)		Urea (mmol/L)		Creatinine (mmol/L)
	Before	After	Before	After	Before	After	Before	After
1	75.12±2.34	109.24±3.42	6.73±1.19	5.04±0.69	5.51±0.33	5.89±0.51	31.30±1.11	30.97±2.52
2	88.24±1.55	114.81±5.10	8.65±2.12	10.32±0.52 *	5.07±0.14	5.82±0.37	49.40±2.54	62.90±3.46 *
3	89.12±3.42	149.65±4.26 *	13.11±1.31 *	27.88±2.37 *	4.53±0.35	6.83±0.40	52.85±2.68	72.10±2.58 *
4	77.50±2.27	76.49±1.33 *	9.53±1.34	5.39±0.89 *	9.61±0.16 *	6.66±0.25	58.80±2.34	47.80±1.19
5	76.21±3.17	84.77±2.50 *	9.07±1.28	3.18±1.41	12.55±0.42	5.66±0.26 *	59.13±1.19	51.40±0.77
6	80.50±1.24	78.10±2.46 *	9.25±1.31	5.10±0.17 *	9.15±0.36	6.65±0.41	51.93±0.76	42.60±0.15
7	85.74±5.31	83.10±3.26 *	8.90±1.19	5.84±0.21 *	14.62±0.54 *	4.98±0.33	57.63±0.50	56.21±0.32

Data are means ± SD for ALT, GGT, urea and creatinine levels of normal rats (Group 1), obese rats (Group 2), diabetic control rats (Group 3), diabetic rats treated with 50 mg/kg bw of C. latifolia fruit:root extracts (Group 4), diabetic rats treated with 100 mg/kg bw of C. latifolia fruit:root extracts (Group 5), diabetic rats treated with 200 mg/kg bw of C. latifolia fruit:root extracts (Group 6), and diabetic rats treated with 10 mg/kg bw of glibenclamide (Group 7).
Significant difference is at *𝑃<0.05 when compared with diabetic control rats (Group 3).