Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels

Figure 4

Effects of TIIA and CT on hypoxia-induced increase in mitochondrial superoxide production. (a) Cell images illustrate MitoSOX (red) and DAPI (blue) in each group. (b) The quantified value of MitoSOX fluorescence intensity. Represented data are mean value of 500 each cells with 5 independent experiments. ^#𝑃<0.05  versus hypoxia, ^##𝑃<0.01  versus hypoxia, ^###𝑃<0.001  versus hypoxia, and ***𝑃<0.001 versus normoxia.

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