Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels

<table>Effects of TIIA and CT on hypoxia-induced increase in intracellular nitric oxide production. (a) Cell images illustrate DAF-2 (green) and DAPI (blue) in each group. (b) Quantitative DAF-2 fluorescence intensity. Represented data are mean value of 500 each cells with 3 independent experiments (<svg height="11.125" id="M51" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>  <i>versus hypoxia</i>,  ***<svg height="11.375" id="M53" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.875 11.375" width="66.875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>  <i>versus normoxia.  </i></table>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels 

Figure 6 | Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels 