Table 4: Meta-analysis of acupuncture for posttraumatic stress disorder. PTSD: posttraumatic stress disorder; CAPS, clinician-administered PTSD scale; HAMD, Hamilton depression rating scale; HAMA, Hamilton anxiety rating scale; EA, electro-acupuncture; moxa, moxibustion; SSRI, selective serotonin reuptake inhibitors;
(a) PTSD scale (CAPS).

Study or subgroupEA + MoxaSSRIMean differenceMean difference
Mean SDTotal MeanSDTotal Weight IV, random, 95% CI IV, random, 95% CI

Zhang et al., 2010 [25] −36.1521.7269−35.5822.12691.0%−0.57 [−7.88, 6.74]615857.tab.002
Zhang et al., 2010 [26]−17.171.8446−13.951.764699.0%−3.22 [−3.96, −2.48]
Total (95% CI)115115100.0%−3.19 [−3.93, −2.46]
Heterogeneity: = 0.00, = 0.50, df = 1 ( = 0.48); = 0%
Test for overall effect: = 8.55 ( 0.00001)

(b) Depression (HAMD).

Study or subgroupEA + MoxaSSRIMean differenceMean difference
Mean SDTotal MeanSDTotal Weight IV, random, 95% CI IV, random, 95% CI

Zhang et al., 2010 [25] −7.425.5869−6.555.1696.2%−0.87 [−2.65, 0.91]615857.tab.003
Zhang et al., 2010 [26]−7.270.9346−5.450.914693.8%−1.82 [−2.20, −1.44]
Total (95% CI)115115100.0%−1.76 [−2.21, −1.31]
Heterogeneity: = 0.02, = 1. 04,df = 1 ( = 0.31); = 4%
Test for overall effect: = 7.72 ( 0.00001)

(c) Anxiety (HAMA).

Study or subgroupEA + MoxaSSRIMean differenceMean difference
Mean SDTotal MeanSDTotal Weight IV, random, 95% CI IV, random, 95% CI

Zhang et al., 2010 [25] −6.515.2669−6.085.43692.9%−0.43 [−2.21, 1.35]615857.tab.004
Zhang et al., 2010 [26]−5.480.7546−4.320.754697.1%−1.16 [−1.47, −0.85]
Total (95% CI)115115100.0%−1.14 [−1.44, −0.84]
Heterogeneity: = 0.00, = 0.62, df = 1 ( = 0.43); = 0%
Test for overall effect: = 7.39 ( 0.00001)