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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 630723, 11 pages
Systemic Revealing Pharmacological Signalling Pathway Networks in the Hippocampus of Ischaemia-Reperfusion Mice Treated with Baicalin
1Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beixiange 5, Xicheng District, Beijing 100053, China
2Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Dongzhimen, Beijing 100700, China
3Geriatric Department, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Dongzhimen, Beijing 100007, China
Received 17 May 2013; Accepted 26 July 2013
Academic Editor: Wei Jia
Copyright © 2013 Haixia Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Supplementary Table 3: Presents the ten most significant biological processes identified by enrichment analysis in the BA and vehicle groups (all P<0.05).
Supplementary Table 4: Shows the ten most significant molecular functions in the BA and vehicle groups (all P<0.05).
Supplementary Table 5: Presents the ten most significant cellular components associated with the BA and vehicle groups (all P<0.05).
Supplementary Table 5A: Presents the ten most statistically significant pathways, based on the MetaCoreTM pathway map analysis (all P<0.05).
Supplementary Table 6: Presents the nine networks associated with cerebral ischemia after BA treatment, each with 150 nodes.
Supplementary Table 7 and Supplementary Figure 1: Presents the six networks associated with cerebral ischemia in the vehicle group, each with 150 nodes.
Supplementary Figure 2: shows that sub network 3 primarily consisted of ZAK, LDB1, TCF12, WIF1, and Kallikrein 1, and that its major functions were intracellular signal transduction and cell surface receptor linked signalling pathway.