Resveratrol Inhibits Alpha-Melanocyte-Stimulating Hormone Signaling, Viability, and Invasiveness in Melanoma Cells

<table>Expression of nuclear and cytosolic MITF in B16 cells with <i>α</i>-MSH (10 nM), STI571 (20 <i>μ</i>M), and/or resveratrol (15 <i>μ</i>M) treatment by using the Western blot analysis. The relative values normalized to the internal control GAPDH (cytosol) and histone H3 (nuclear) were calculated from three independent experiments. Data were expressed as mean ± SE. <svg height="13.95" id="M9" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.324997 13.95" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> as compared to the control group. Res: resveratrol; STI: STI571. </table>

Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: Resveratrol Inhibits Alpha-Melanocyte-Stimulating Hormone Signaling, Viability, and Invasiveness in Melanoma Cells 