Hepatoprotective Activity of Methanolic Extract of Bauhinia purpurea Leaves against Paracetamol-Induced Hepatic Damage in Rats

Table 4

Effect of MEBP pretreatment on ALT, AST and ALP (U/L) level.

Treatment	Dose (mg/kg)	ALT (U/L)	AST (U/L)	ALP (U/L)
Control	—	15.83 ± 2.862	95.13 ± 5.924	115.7 ± 6.994
PCM control (neg)		1714 ± 142.2^a	3008 ± 210.7^a	330.0 ± 42.35^a
Silymarin (pos)	200	588.1 ± 193.7^ab	959.2 ± 338.8^ab	195.5 ± 11.06^ab
MEBP	50	1222 ± 187.7^a	2407 ± 294.9^a	347.0 ± 29.40^a
	250	1096 ± 221.1^ab	2076 ± 409.4^ab	264.8 ± 29.77^a
	500	867.7 ± 101.2^ab	1730 ± 256.6^ab	256.3 ± 13.91^a

Values are expressed as means ± S.E.M. of six replicates.
aData differed significantly (𝑃<0.05) when compared to the normal control group within each respective column.
bData differed significantly (𝑃<0.05) when compared to the negative control group within each respective column.