Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy

Figure 3

Addition of SAMC attenuated intrinsic apoptotic pathway components through p53 during the development of NAFLD. Protein expressions of (a) phosphorylated and total p53, (b) cytochrome c, (c) Bcl-2, (d) Bcl-XL, (e) Bak1, and (f) Bax were measured by Western blot and then quantified by ImageJ software. Data presented are expressed as mean ± SEM (𝑛=7), and experimental groups marked by different letters represented significant differences between groups at 𝑃<0.05 (Kruskal-Wallis test followed by Dunn’s post hoc test). N + S: NAFLD + SAMC cotreatment.

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