Ginsenoside Rh2 Downregulates LPS-Induced NF-κB Activation through Inhibition of TAK1 Phosphorylation in RAW 264.7 Murine Macrophage

Figure 2

Effects of ginsenoside Rh2 on CD14/TLR4 expression. RAW 264.7 cells were pretreated with indicated concentrations of ginsenoside Rh2 for 1 h prior to incubation of LPS (1 μg/mL) for 24 h. CD14 and TLR4 were determined by western blot. Each immunoreactive band was digitized and expressed as a ratio of α-tubulin levels. The ratio of the normal group band was set to 1.00. Data are expressed as mean ± SD of three independent experiments. **𝑃<0.01, *𝑃<0.05, significantly different when compared with LPS-stimulated cells.

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