A Computational Drug-Target Network for Yuanhu Zhitong Prescription
Figure 7
Antidepressant-like effect of YZP. (a) Effects of YZP and fluoxetine (Fluox) on locomotor counters in locomotor activity. Significant differences: * and **, compared with the untreated control group. (b) Antidepressant-like effect of YZP (4 g/kg, 8 g/kg and 16 g/kg, resp.) on the FST in mice. Animals were given i.g. YZP or fluoxetine before the tests. The duration of immobility in FST during the last 4 min of the test was recorded. No significant difference was found between Fluoxetine and YZP treated groups. Values were expressed as the mean ± SEM and analyzed using one-way ANOVA. Significant differences: * and **, compared with the untreated control group. (c) Antidepressant-like effect of YZP (4 g/kg, 8 g/kg, and 16 g/kg, resp.) on the TST in mice. The duration of immobility in TST during the 6 min of the test was recorded. No significant difference was found between Fluoxetine and YZP treated groups. Values were expressed as the mean ± SEM and analyzed using one-way ANOVA. Significant differences: * and **, compared with the untreated control group.
