Table 2: The eHiTS scores of potential targets.

NOGene namePDBProtein nameCompoundseHiTS score

1ESR11R5KEstrogen receptorcorydaline
2DRD33PBLD(3) dopamine receptorcorydaline
3CHRM23UONMuscarinic acetylcholine receptor M2corydaline
4CHRM34DAJMuscarinic acetylcholine receptor M3corydaline
5CRYZ1YB5Quinone oxidoreductaseoxypeucedanin
6TOP2A1ZXNDNA topoisomerase 2-alphaoxypeucedanin_M1
7VKORC13KP9Vitamin K epoxide reductase complex subunit 1byakangelicin
8ESR21QKMEstrogen receptor betaα-Allocryptopine
9ACE1UZFAngiotensin-converting enzymetetrahydroberberine
10ADRA1A3SN6Alpha-1A adrenergic receptortetrahydropalmatine
11OPRK14DJHKappa-type opioid receptortetrahydropalmatine
12HRH13RZEHistamine H1 receptortetrahydropalmatine
13ADRA2A3RFMAlpha-2A adrenergic receptorTetrahydropalmatine_M2
14ABCC82BBOATP-binding cassette transporter subfamily C member 8protopine_M1
15KCNJ83HFCATP-sensitive inward rectifier potassium channel 8protopine_M1
16BCHE2WILCholinesteraseprotopine_M1
17RNASE31DYTEosinophil cationic proteinprotopine_M1