Salidroside Improves Homocysteine-Induced Endothelial Dysfunction by Reducing Oxidative Stress

Table 1

ACh-induced relaxations under various pharmacological treatments.

Treatment	pD2	𝐸max (%)
ACh relaxation
Control	7.03 ± 0.06	93.3 ± 1.5
Homocysteine (Hcy)	6.42 ± 0.32	8.2 ± 5.1*
Salidroside 100 µM + Hcy	6.90 ± 0.12	40.4 ± 6.1^#
Salidroside 300 µM + Hcy	6.97 ± 0.21	62.8 ± 9.3^#
Tiron + Hcy	7.29 ± 0.10	88.0 ± 3.7^#
DPI + Hcy	6.72 ± 0.06	52.7 ± 3.9^#
SNP relaxation
Control	7.55 ± 0.07	102 ± 0.9
Homocysteine (Hcy)	7.67 ± 0.08	101 ± 0.6
Salidroside 300 µM + Hcy	7.85 ± 0.07	101 ± 1.2

Results are means ± SEM of 5–7 separate experiments. *P < 0.05 versus control and ^#P < 0.05 versus homocysteine.