Research Article

Protective Effects of Lycium barbarum Polysaccharides on Testis Spermatogenic Injury Induced by Bisphenol A in Mice

Figure 1

Development of spermatogenic cells in seminiferous tubules of mice testis (Bar = 100 μm). (a) Control group: the histological structure of seminiferous tubules is normal with 5–7 layers of closely and orderly arrayed spermatogenic cells. (b) BPA group: some of the spermatogenic cells desquamate or vanish. The spermatogenic cells array loosely and disorderly. There are gaps between spermospores and primary spermatocytes. (c) 50 mg/kg LBP (L) group: the spermatogenic cells are less closely arrayed, and some of the spermatogenic cells desquamate. (d) 100 mg/kg LBP (M) group: the spermatogenic cells are less closely arrayed and different stages of spermatogenic cells can be identified. (e) 200 mg/kg LBP (H) group: the spermatogenic cells in this group are more closely and tightly arrayed than cells in 50 mg/kg and 100 mg/kg group. The histological structure of seminiferous tubules is clear. The gaps between cells were larger than usual (the thick black arrow); the seminiferous tubules spaces were bigger (the thin black arrow); the spermatogenic cells array loosely and disorderly, and some spermatoggenic cells desquamated (the thick white arrow); the cells array more orderly and closely than other groups except the control group (the thin white arrow).
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