Autonomic Nervous System Mediates the Hypotensive Effects of Aqueous and Residual Methanolic Extracts of Syzygium polyanthum (Wight) Walp. var. polyanthum Leaves in Anaesthetized Rats

Table 2

Recovery time (in minutes) for 20, 30, 40, 70, and 100 mg/kg AESP and met-AESP in WKY and SHR.

		Recovery time (min)
Dose (mg/kg)		AESP				Met-AESP
		MAP	SBP	DBP	HR	MAP	SBP	DBP	HR
20	WKY	2	2	2	n.a	n.a	n.a	n.a	n.a
	SHR	1	1	2	n.a	n.a	n.a	n.a	n.a
30	WKY	3	3	3	n.a	n.a	n.a	n.a	n.a
	SHR	1	1	2	n.a	3	3	4	n.a
40	WKY	3	3	3	n.a	4	4	4	n.a
	SHR	2	2	2	n.a	4	4	4	n.a
70	WKY	4	4	4	n.a	4	4	4	n.a
	SHR	2	2	2	n.a	4	5	6	n.a
100	WKY	5	6	6	17	5	6	5	n.a
	SHR	3	4	4	5	4	4	5	n.a

Recovery time: the time when the averaged readings of MAP, SBP, DBP, and HR were no longer significantly different as compared to the initial baseline values. MAP: recorded mean arterial blood pressure in millimetres of mercury, HR: recorded heart rate in beats per minute, AESP: aqueous extract of S. polyanthum leaves, met-AESP: residual methanolic extract of S. polyanthum leaves, WKY: Wistar-Kyoto rats, SHR: spontaneously hypertensive rats, n.a: there were no changes observed in the baselines of MAP, SBP, DBP, and HR upon administration of the respective doses.