Rhodiola crenulata Extract Alleviates Hypoxic Pulmonary Edema in Rats

Figure 1

RCE significantly attenuated hypoxia-induced pulmonary edema and alveolar extravascular protein. Effect of RCE on (a) W/D weight ratio and (b) BALF protein concentration. The rat control groups were treated with saline (control) or RCE under normoxia. The rat hypoxia groups received hypoxia treatment alone (H) or in combination with different doses of RCE (H + RCE). Results represent mean ± SEM (𝑛=6). ^∗𝑃<0.05; ^∗∗𝑃<0.01; ^∗∗∗𝑃<0.001 versus control; ^#𝑃<0.05; ^##𝑃<0.01; ^###𝑃<0.001  versus hypoxia (H).

(a)

(b)