Efficacy and Safety of Acupuncture in Preterm and Term Infants

Table 1

Risk of bias assessment of randomized controlled trials investigating acupuncture in preterm and term infants.

Study	Study population	Comparison	Primary outcome measures	Sequence generation	Allocation concealment	Blinding of participants, personnel, and outcome	Incomplete outcome data	Selective outcome reporting	Funding bias
Ecevit et al. [28]	Preterm infants (𝑛=10)	Breast milk only or breast milk and acupuncture	Crying duration during heel prick for blood gas analysis	Unclear	Unclear	Unclear	Unclear	Unclear	Unclear
Landgren et al. [19, 35]	2–8 weeks old infants (𝑛=90)	Structured program versus structured program and needle acupuncture	Remission of infantile colic	Low	Low	Low	Low	Low	Low
Reinthal et al. [20]	Median 6 weeks old infants (𝑛=40)	Intervention versus control group	Crying intensity, frequency, duration of, crying and; pain related behavior	Unclear	Unclear	Unclear	Low	Low	Low