Hepatoprotective Role of Ethanolic Extract of Vitex negundo in Thioacetamide-Induced Liver Fibrosis in Male Rats

Table 1

Effect of TAA, SY, and VN ethanolic extract on liver function test.

Group	ALT (IU/L)	AST (IU/L)	AP (IU/L)	Bilirubin (umol/L)	Total protein (mg/dL)	Albumin (g/L)
Normal	43.66±4.9^b	23.66±3.1^b	87.66±25.08^b	4.83±2.6^b	70.167±2.9	41±1.5^b
TAA	89.83±17.9^a	311.33±50.05^a	223.8±77.5^a	19.83±6.4^a	69±2.5	18.33±4.8^a
VN 300	50.16±8.7^b	31.16±5.60^b	81.66±48.3^b	5.66±1.9^b	74.167±4.16	39±3.2^b
VN 100	55.33±8.1^b	32.33±5.64^b	101±42.23^b	7±1.5^b	78.3±3.72^a,b	38.83±4.07^b
VN 300 + TAA	60±4.8^b	128.83±60.0^b,a	107±8.5^b	9.33±1.0^b	72±2.6	35.6±4.8^b
VN 100 + TAA	62±4.1^a,b	152.5±47.0^b,a	136±39.6^b	9.16±1.4^b	72.83±3.31	31.83±10.6^b
SY + TAA	59.16±4.5^b	154.33±62.7^b,a	139±37.5^b	8±1.6^b	75.167±4.2	36.83±5.6^b

The data were stated as mean ± SEM. Means with different superscripts are significantly different. ^a𝑃<0.05 versus normal control group and ^b𝑃<0.05 versus TAA control group. SY stands for Silymarin (standard hepatoprotective drug).