Baicalein, Ethyl Acetate, and Chloroform Extracts of Scutellaria baicalensis Inhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A Viruses
Figure 2
Time-of-addition inhibition of S. baicalensis extracts on pandemic 2009 H1N1 influenza A virus yields. Indicated extracts (0, 10, 100, or 1000 μg/mL) treated MDCK cells during (simultaneous treatment) (a) and 1 h after (postinfection treatment) (b) infections of pandemic 2009 H1N1 virus. After 36 h incubation, virus-induced cytopathic effect was photographed, using reverse-phase light microscopy. (c and d) Virus yield was determined real-time RT-PCR; value was calculated by subtracting value for viral load in cultured media of treated infected cells from value in those of mock-infected cells.
