Prunus mume and Lithospermum erythrorhizon Extracts Synergistically Prevent Visceral Adiposity by Improving Energy Metabolism through Potentiating Hypothalamic Leptin and Insulin Signalling in Ovariectomized Rats
Figure 1
Phosphorylation of STAT3, AMPK, and Akt in the hypothalamus. Control, OVX rats fed high fat diet (HFD) with 5% cellulose; PMA, OVX rats fed HFD with 5% Prunus mume; LES, OVX rats fed HFD and 5% Lithospermum erythrorhizon; PMA+LES, OVX rats fed HFD with 2.5% PMA and 2.5% LES. Sham, Sham rats fed HFD with 5% cellulose. The intensity of phosphorylation of STAT3, AMPK, and Akt proteins was corrected by that of respective total unphosphorylated proteins to be expressed as relative intensity (arbitrary unit). *Significantly different among the groups of OVX rats at . Different superscripts on the bars of each variable indicate significant differences in each variable. †Significant difference between OVX rats and Sham rats.
