Research Article

Prunus mume and Lithospermum erythrorhizon Extracts Synergistically Prevent Visceral Adiposity by Improving Energy Metabolism through Potentiating Hypothalamic Leptin and Insulin Signalling in Ovariectomized Rats

Figure 2

Serum glucose levels and area under the curve (AUC) of serum glucose and insulin during oral glucose tolerance test (OGTT). Control, OVX rats fed high fat diet (HFD) with 5% cellulose; PMA, OVX rats fed HFD with 5% Prunus mume; LES, OVX rats fed HFD and 5% Lithospermum erythrorhizon; PMA+LES, OVX rats fed HFD with 2.5% PMA and 2.5% LES. Sham, Sham rats fed HFD with 5% cellulose. (a) Changes of serum glucose levels during OGTT. (b) The average of the AUC of glucose and insulin during the first part (0–40 min) and second part (40–120 min) of OGTT. Each dot and bar represents the mean ± SD . *Significantly different among the groups of OVX rats at .   Different superscripts on the bars of each variable indicate significant differences in each variable. Significant difference between OVX rats and Sham rats.
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750986.fig.002b
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