Prunus mume and Lithospermum erythrorhizon Extracts Synergistically Prevent Visceral Adiposity by Improving Energy Metabolism through Potentiating Hypothalamic Leptin and Insulin Signalling in Ovariectomized Rats
Figure 3
Glucose and lipid metabolism in the liver and skeletal muscles. Control, OVX rats fed high fat diet (HFD) with 5% cellulose; PMA, OVX rats fed HFD with 5% Prunus mume; LES, OVX rats fed HFD and 5% Lithospermum erythrorhizon; PMA+LES, OVX rats fed HFD with 2.5% PMA and 2.5% LES. Sham, Sham rats fed HFD with 5% cellulose. (a) Stored glycogen levels. (b) Triglyceride accumulation. (c) mRNA expression of CPT-1, SREBP-1c, FAS, and ACC in the liver. (d) mRNA expression of UCP-1 in the brown adipose tissues and UCP-2 and UCP-3 in the quadriceps muscles. *Significantly different among the groups of OVX rats at . Different superscripts on the bars of each variable indicate significantly differences in each variable. †Significant difference between OVX rats and Sham rats.
