Table 1: Effects of anthropometric and biochemical parameters in obese subjects after a VLCD intervention.

BaselineWeek 4Week 8Change from baseline to Week 8P

Weight, Kg96.1 ± 2.790.1 ± 2.6*87.4 ± 2.5*−8.7 ± 0.6<0.0001
BMI, Kg/m232.6 ± 0.630.6 ± 0.6*29.7 ± 0.6*−3.0 ± 0.2<0.0001
Waist, cm104.5 ± 1.7100.7 ± 1.5*98.6 ± 1.4*−5.9 ± 1.2<0.0001
SBP, mmHg135.2 ± 2.8124.1 ± 2.0*121.7 ± 2.0*−13.1 ± 2.8<0.0001
DBP, mmHg82.7 ± 1.776.7 ± 1.5*73.9 ± 1.6*−8.2 ± 1.6<0.0001
ALT, U/L 42.9 ± 5.131.6 ± 3.5*22.3 ± 1.6*−20.6 ± 5.20.002
AST, U/L 26.2 ± 1.923.0 ± 1.5**20.3 ± 1.5*−6.0 ± 1.70.001
γ-GT, U/L 55.1 ± 6.527.2 ± 2.4*27.8 ± 3.5*−30.4 ± 6.3<0.0001
Serum uric acid, μmol/L395.1 ± 13.5382.5 ± 14.2369.2 ± 17.0**−26.1 ± 10.00.035
UACR, μg/mg 8.7 ± 1.07.5 ± 0.97.1 ± 0.7−1.9 ± 0.90.059
TC, mmol/L 5.12 ± 0.124.60 ± 0.13*4.79 ± 0.14*−0.37 ± 0.14<0.0001
TG, mmol/L 1.98 ± 0.231.11 ± 0.10*1.08 ± 0.09*−0.98 ± 0.23 <0.0001
HDL, mmol/L 1.15 ± 0.041.09 ± 0.03**1.19 ± 0.040.02 ± 0.030.01
LDL, mmol/L 3.09 ± 0.123.01 ± 0.123.13 ± 0.130.05 ± 0.100.407
NEFA, μmmol/L729.8 ± 34.9729.3 ± 43.2574.7 ± 37.0*−166.2 ± 47.60.001
BHA, mmol/L0.06 ± 0.010.56 ± 0.13*0.24 ± 0.07*0.15 ± 0.060.004

Data are presented as mean ± standard error (SE). BMI: body mass index; SBP: systolic blood pressure; DBP: systolic bold pressure; TC: total cholesterol; TG: triacylglycerol; HDL: high density lipoprotein; LDL: low density lipoprotein; NEFA: non-esterified fatty acid; BHA: β-hydroxybutyric acid; ALT: alanine aminotransferase; AST: aspartate aminotransferase; γ-GT: γ-glutamyl transferase; UACR: urine microalbumin creatinine ratio. P: changes of sequential data within experiments from baseline to week 8. Significant difference observed versus baseline: ; .