Unexpected Nephrotoxicity in Male Ablactated Rats Induced by Cordyceps militaris: The Involvement of Oxidative Changes
Figure 3
Micrographs showing histopathological changes in kidneys. (a) Normal glomeruli and renal tubules, the control group. (b) Proteinaceous effusion in the glomerular capsule as well as focal proteinaceous casts in the tubular lumina, male rats at 3 g/kg group. (c) Arrows indicate larger cells with one more nucleolus, male rats at 3 g/kg group. (d) Extensive necrosis and sloughing of proximal tubular epithelium. # indicates necrotic debris, and * indicates tubular vacuolar degeneration, male rats at 3 g/kg group. (e) Dilated tubular epithelium without evidence of nuclear detail, male rats at 3 g/kg group. (f) Slight infiltration and moderate edema, female rats at 3 g/kg group.
