Unexpected Nephrotoxicity in Male Ablactated Rats Induced by Cordyceps militaris: The Involvement of Oxidative Changes

Table 4

Organ-to-body weight ratios of rats treated with CCM for 28 days.

Treatment (g/kg)	Liver (%)	Spleen (%)	Kidney (%)	Testis (%)	Ovary (%)
Male rats
0	3.44±0.19	0.25±0.03	0.86±0.02	0.88±0.07
1	3.39±0.19	0.24±0.03	0.89±0.07	0.89±0.09
2	3.33±0.22	0.24±0.02	0.94±0.11	1.03±0.09^∗∗
3	3.37±0.12	0.24±0.02	0.91±0.06^∗	1.04±0.09^∗∗
Female rats
0	3.52±0.45	0.23±0.04	0.80±0.13		0.06±0.01
1	3.46±0.34	0.22±0.02	0.84±0.11		0.05±0.01
2	3.36±0.16	0.22±0.04	0.73±0.05		0.06±0.01
3	3.55±0.17	0.22±0.04	0.77±0.06		0.06±0.01

Each value is expressed as mean ± SD (𝑛=10/sex/dose).
^∗𝑃<0.05;  ^∗∗𝑃<0.01.