Scopoletin Inhibits Rat Aldose Reductase Activity and Cataractogenesis in Galactose-Fed Rats
Figure 5
Immunofluorescence stained AR. Representative immunostained AR in lenses from the normal rats (NOR), the vehicle-treated galactose-fed rats (GAL), the galactose-fed rats treated with scopoletin at concentration 10 mg/kg (SCO-10), and the galactose-fed rats treated with scopoletin at concentration 50 mg/kg (SCO-50). AR was strongly immunoreactive in the cytoplasm of the lens epithelial cells and lens cortical fibers. The negative control section was incubated with nonimmune mouse IgG and remained unstained.
