Research Article

Postischemic Long-Term Treatment with Qiangli Tianma Duzhong Capsule Improves Brain Functional Recovery via the Improvement of Hemorrheology and the Inhibition of Platelet Aggregation in a Rat Model of Focal Cerebral Ischemia

Figure 2

Post-ischemic long-term treatment with TMDZ reduces brain tissue loss after ischemic stroke. Animals underwent 2 h MCAO and reperfusion and received either an oral administration of TMDZ or vehicle (distilled water) at 2 h MCAO, 4 h reperfusion, and every day later for 28 days. The representative images of the whole brain and the sliced brain (a). The volume of right hemisphere (injured hemisphere) was indicated as the percentage of ipsilateral hemisphere volume of the contralateral hemisphere volume (indirect volume calculation) (b). Values shown are mean ± S.D., . Statistical analysis was carried out with one-way ANOVA followed by a post hoc Tukey test. # and ## versus sham-operated group (Sham); ** versus ischemic-reperfusion control group (IR Control).
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(a)
795365.fig.002b
(b)