Research Article

Postischemic Long-Term Treatment with Qiangli Tianma Duzhong Capsule Improves Brain Functional Recovery via the Improvement of Hemorrheology and the Inhibition of Platelet Aggregation in a Rat Model of Focal Cerebral Ischemia

Table 2

Hemorrheology parameters in normal rats. Animals received an oral administration of TMDZ or vehicle (distilled water) for 28 days, and then the blood was obtained, and hemorrheology parameters were detected. Values shown are mean ± SD, . TMDZ did not change any of the hemorrheology parameters after normal rats were administrated with TMDZ for 28 days.

ParametersControlTianma Duzhong capsule
44.5 mg/kg89 mg/kg178 mg/kg

WBV: low shear (mPas) ∣ 10 s−1
WBV: moderate shear (mPas) ∣ 60 s−1
WBV: high shear (mPas) ∣ 150 s−1
PV
WBRV: low shear
WBRV: moderate shear
WBRV: high shear
Fb
HCT (%)
ESR(MM/H)
ESRK
RBCAI
RBCRI
RBCDI
RBCEI

WBV: whole blood viscosity; WBRV: whole blood reduced viscosity; PV: Plasma viscosity; Fb: fibrinogen; HCT: hematocrit; ESR: erythrocyte sedimentation rate; ESRK: erythrocyte sedimentation rate equation K value; RBCAI: red blood cell aggregation index; RBCRI: red blood cell rigidity index; RBCDI: red blood cell deformation index; RBCEI: red blood cell electrophoresis index.