Research Article

Blockade of Adrenal Medulla-Derived Epinephrine Potentiates Bee Venom-Induced Antinociception in the Mouse Formalin Test: Involvement of Peripheral β-Adrenoceptors

Figure 2

Graphs illustrating the effect of chemical sympathectomy with 6-OHDA in combination with DBV on the formalin test. This figure shows that chemical sympathectomy itself [(6-OHDA) + Veh + F] did not change formalin-induced pain behavior as compared to the vehicle-injected control group (Veh + Veh + F) during either the early or late phase of the formalin test. Injection of 6-OHDA in combination with DBV [(6-OHDA) + DBV + F] also did not affect formalin-induced pain behavior as compared to a DBV-injected control group (Veh + DBV + F, NS; no significance).
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