Research Article
Combination Therapy of Sophoraflavanone B against MRSA: In Vitro Synergy Testing
Table 6
Results of the combination of SPF-B + CIP against MRSA.
| | S. aureus | Agent | MIC (μg/mL) | FIC | FICI | Outcome | | Alone | SPF-B + CIP |
| | ATCC 33591 | SPF-B | 15.6 | 3.9 | 0.25 | 0.5 | Synergy | | CIP | 1,000 | 250 | 0.25 | | DPS-1 | SPF-B | 15.6 | 3.9 | 0.25 | 0.31 | Synergy | | CIP | 500 | 62.5 | 0.06 | | DPS-2 | SPF-B | 31.25 | 3.9 | 0.06 | 0.56 | Partial synergy | | CIP | 1,000 | 500 | 0.5 | | DPS-3 | SPF-B | 31.25 | 15.6 | 0.25 | 0.5 | Synergy | | CIP | 500 | 125 | 0.25 | | DPS-4 | SPF-B | 31.25 | 15.6 | 0.25 | 0.5 | Synergy | | CIP | 250 | 62.5 | 0.25 | | DPS-5 | SPF-B | 31.25 | 7.8 | 0.25 | 0.75 | Partial synergy | | CIP | 250 | 125 | 0.5 |
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