Nymphaeol-A Isolated from Okinawan Propolis Suppresses Angiogenesis and Induces Caspase-Dependent Apoptosis via Inactivation of Survival Signals
Figure 4
Nymphaeol derivatives inhibit angiogenesis in vitro. HUVECs were sandwiched between two layers of collagen gel and induced to form blood-vessel-like tubes. HUVECs were treated with the indicated concentrations of each compound for 36 h.