Research Article
Neurite Outgrowth and Neuroprotective Effects of Quercetin from Caesalpinia mimosoides Lamk. on Cultured P19-Derived Neurons
Table 1
Antioxidant and anticholinesterase activities of isolated compounds.
| | Antioxidant |
Anticholinesterase (using purified enzyme from E. electricus) |
Anticholinesterase (using neuroblastoma cell) | | % inhibition (at 100 µg/mL) | IC50 (µg/mL) | % inhibition (at 100 µg/mL) | IC50 (µg/mL) | % inhibition (at 100 µg/mL) | IC50 (µg/mL) |
| Gallic acid | 94.76 ± 0.51 | 4.83 ± 0.02 | 73.64 ± 0.06 | 12.73 ± 0.56 | 90.67 ± 2.66 | 2.79 ± 0.17 |
| Quercetin | 92.61 ± 0.99 | 3.18 ± 0.07 | 80.94 ± 2.52 | 56.84 ± 2.64 | 82.0 ± 3.34 | 36.60 ± 2.78 |
| Positive control |
Trolox: IC50 12.54 ± 0.89 Ascorbic acid: IC50 10.52 ± 0.48 |
Galanthamine IC50 0.81 ± 0.04 |
Galanthamine IC50 0.23 ± 0.02 |
|
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Values are mean ± SEM ().
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