Neurite Outgrowth and Neuroprotective Effects of Quercetin from Caesalpinia mimosoides Lamk. on Cultured P19-Derived Neurons

Table 1

Antioxidant and anticholinesterase activities of isolated compounds.

	Antioxidant		Anticholinesterase; (using purified enzyme from E. electricus)		Anticholinesterase; (using neuroblastoma cell)
	% inhibition; (at 100 µg/mL)	IC50 (µg/mL)	% inhibition; (at 100 µg/mL)	IC50 (µg/mL)	% inhibition; (at 100 µg/mL)	IC50 (µg/mL)
Gallic acid	94.76 ± 0.51	4.83 ± 0.02	73.64 ± 0.06	12.73 ± 0.56	90.67 ± 2.66	2.79 ± 0.17
Quercetin	92.61 ± 0.99	3.18 ± 0.07	80.94 ± 2.52	56.84 ± 2.64	82.0 ± 3.34	36.60 ± 2.78
Positive control	Trolox: IC50 12.54 ± 0.89; Ascorbic acid: IC50 10.52 ± 0.48		Galanthamine; IC50 0.81 ± 0.04		Galanthamine; IC50 0.23 ± 0.02

Values are mean ± SEM (𝑛=3).