Alternanthera sessilis Red Ethyl Acetate Fraction Exhibits Antidiabetic Potential on Obese Type 2 Diabetic Rats

Table 1

Effect of ASEAF on the insulin resistant state of the diabetic rats. The insulin sensitivity indexes (HOMA and QUICKI) were used to quantify the effect. The index values before and after 250 mg/kg ASEAF oral administration were shown.

	HOMA index		QUICKI
	Before	After	Before	After
Negative	1.563 ± 0.169	1.197 ± 0.038	0.280 ± 0.003	0.289 ± 0.001
Pioglitazone	1.746 ± 0.348	0.646 ± 0.103^a,b	0.279 ± 0.005	0.316 ± 0.006^a,d
ASEAF	1.616 ± 0.302	0.689 ± 0.109^a,c	0.282 ± 0.006	0.313 ± 0.005^a,b

Data shown are the calculated index values and are presented as mean ± SEM, 6 rats (𝑛=6) per group; ^a𝑃<0.001 versus negative control group; ^b𝑃<0.01; ^c𝑃<0.05; ^d𝑃<0.001 versus before treatment.