Protective Effect of Standardized Extract of <i>Ginkgo biloba</i> against Cisplatin-Induced Nephrotoxicity

<table>EGb inhibited the tubular apoptosis in rats induced by CDDP. TUNEL assay was performed from rats kidney: (a) control rats; (b) EGb-only rats (200 mg/kg); (c) CDDP-treated rats (10 mg/kg); (d) rats treated with EGb plus CDDP. As described in the methods, fragmented DNA labelling corresponds to green spots. (e) Quantitative analysis of TUNEL staining. Data represent mean ± S.D. from three independent experiments. <svg height="13.95" id="M50" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.324997 13.95" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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q0 -76 10 -138.5t37 -107.5t69 -45q32 0 55.5 25t35.5 68.5t17.5 91.5t5.5 105t-5.5 105.5t-18 92t-36 68t-56.5 24.5z" id="x30"></path></g><g transform="matrix(.017,-0,0,-.017,58.093,13.688)"><path d="M153 550l-26 -186q79 31 111 31q90 0 141.5 -51t51.5 -119q0 -93 -89 -166q-85 -69 -173 -71q-32 0 -61.5 11.5t-41.5 23.5q-18 17 -17 34q2 16 22 33q14 9 26 -1q61 -50 124 -50q60 0 93 43.5t33 104.5q0 69 -41.5 110t-121.5 41q-53 0 -102 -20l38 305h286l6 -8
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</svg> versus saline; <svg height="15.775" id="M51" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 67.387497 15.775" width="67.387497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus CDDP. Original magnification, ×100.</table>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Protective Effect of Standardized Extract of <i>Ginkgo biloba</i> against Cisplatin-Induced Nephrotoxicity 

Evidence-Based Complementary and Alternative Medicine

Protective Effect of Standardized Extract of Ginkgo biloba against Cisplatin-Induced Nephrotoxicity

Figure 3