Protective Effect of Standardized Extract of Ginkgo biloba against Cisplatin-Induced Nephrotoxicity

Figure 7

Effect of EGb and furosemide on urine output. In CDDP group, 10 mg/kg of CDDP was injected intraperitoneally to rats at time zero. CDDP + EGb group, EGb for 5 consecutive days through oral gavages and intraperitoneal injection of CDDP once on the 5th day. In CDDP + furosemide group, furosemide solution was infused at a rate of 0.05 mL/min for 20 min before CDDP was injected intraperitoneally. Constant infusion of furosemide was continued for an additional 20 min. Values are mean urine output ± S.D. in each urine collection period.