Use of Propolis Hydroalcoholic Extract to Treat Colitis Experimentally Induced in Rats by 2,4,6-Trinitrobenzenesulfonic Acid

Table 4

The myeloperoxidase activity (MPO) (nm) in the distal colons of rats that received rectal TNBS (to induce colitis) or saline solution (S) after treatment for 5 or 12 days with propolis hydroalcoholic solution (TNBS-P and SP) or mesalazine solution (TNBS-M). The animals were euthanized 7 or 14 days after the colitis was induced. The results are expressed as the mean ± standard deviation (𝑛=5).

MPO activity (OD 450 nm)
Group/time (days)	Day 7	Day 14
S	0.185±0.041^a	0.166±0.071^a
TNBS	0.618±0.161^b	0.659±0.124^b
SP	0.068±0.074^a	0.180±0.097^a
TNBS-P	0.720±0.051^b	0.823±0.029^c
TNBS-M	0.749±0.172^b	0.782±0.046^bc

^a,b,cThe means followed by different letters in the same column are significantly different according a to two-way ANOVA model and the Bonferroni post-test (𝑃<0.05).