Use of Propolis Hydroalcoholic Extract to Treat Colitis Experimentally Induced in Rats by 2,4,6-Trinitrobenzenesulfonic Acid

Table 6

The metaphase index (MetI) in the epithelium of the distal colons of rats that received rectal TNBS (to induce colitis) or saline solution (S) after treatment for 5 or 12 days with propolis hydroalcoholic solution (TNBS-P and SP) or mesalazine.

Group/time	Metaphase Index (MetI) (%)
	Day 7	Day 14
S	6.945 ± 0.8575	8.872 ± 0.7792
TNBS	9.099 ± 2.722	10.51 ± 0.8000
SP	6.373 ± 1.042	5.68 ± 0.827
TNBS-P	7.468 ± 2.029	6.038 ± 1.102^a
TNBS-M	4.528 ± 3.298^a	5.663 ± 1.053^a

^a𝑃<0.05 compared to TNBS in the same column through a one-way ANOVA model and Tukey’s post-test (mean ± standard deviation, 𝑛=4).