Anti-Inflammatory Effects and Mechanisms of Fatsia polycarpa Hayata and Its Constituents
Figure 5
The anti-inflammatory effect of HOEO on TPA-induced ear edema of mice. Mice were treated with TPA on both ears for 1 h, followed by HOEO (300 μg/ear) or indomethacin (500 μg/ear) administration on the right ear, while the left ear was treated with the vehicle. In TPA control, TPA was applied to only the right ear, and both ears were treated with the vehicle at 1 h afterwards. Ear thickness was measured before and at 4 h, 16 h, 20 h, and 24 h after TPA treatment. Data represent the mean ± SD of each group (). (a) The comparison of the thickness of the right ear at different time points. against the same time point in the group of TPA control. (b) The comparison of the thickness of the right ear and the left ear at 24 h after TPA treatment. against the left ear of the same group.
