Active Constituents from Liriope platyphylla Root against Cancer Growth In Vitro

Figure 6

(−)-Liriopein B identified from LPRP-9 inhibits AKT activation. (a) Effect of (−)-Liriopein B on MCF-7 cell growth was measured by MTT assay, which was performed at 48 h after cells exposure to the indicated doses of (−)-Liriopein B. (b) Immunoblots results showing the effect of (−)-Liriopein B on AKT signaling pathway expression by detecting phosphorylation of AKT Thr³⁰⁸, Ser⁴⁷³, and FaxO3a Ser^318/321 in MCF-7 cells treated with drugs at the indicated doses for 24 h.

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