Research Article

Effect of Electroacupuncture on Rat Ischemic Brain Injury: Importance of Stimulation Duration

Figure 3

Statistical summary of EA effects on PU in the ischemic brain. , Ischemia + EA versus Ischemia group during MCAO; , under reperfusion versus during MCAO in the Ischemia group; , Ischemia + EA versus Ischemia group under reperfusion; , Ischemia + EA versus Ischemia group under reperfusion. Note that MCAO sharply decreased PU to ~15% of the basal value (pre-MCAO), while EA for 5–45 min significantly increased the blood flow to ~30% of the baseline. Within 10–15 minutes after reperfusion, PU gradually increased to ~25% of the baseline (pre-MCAO) in the Ischemia group, whereas it rapidly increased to about 90% of the baseline in the EA for 5–30 minutes groups. In sharp contrast, PU was still at the MCAO level, that is, ~15% of the basal value, during the same period after reperfusion in the group of EA for 45 minutes.
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