Table 6: Pharmacokinetic and pharmacodynamic interactions of herbal products/food/dietary supplements with CBZ by direction of interactions.
(a)

Pharmacokinetic interactions with CBZ
Oral bioavailability/plasma level of CBZ
IncreasedDecreasedNo effect

Piperine
Mentat 
Polygonum cuspidatum  
Butter 
Grapefruit juice
Platycodonis Radix 
Pomegranate juice 
Star fruit juice 
Kinnow juice
Alcohol* 
Coca-cola
Nicotinamide
Septilin
Ginkgo biloba
Hu-gan-ning pian
Ispaghula husk
Cassia auriculata Linn.  
Hu-gan-ning pian 
Xiao-cha-hu-tang
Xiao-yao-san
Jia-wei-xiao-yao-san
Soybean
Caffeine
Hypericum perforatum Linn.
Paeoniae Radix
Cardiospermum halicacabum Linn.
Berberine
Xiao-qing-long-tang
Chai-hu-jia-long-gu-mu-li-tang
Acorus calamus Linn.
Honey
Melatonin
Folinic acid

 *In alcoholics, not healthy volunteers; study type: human study (bold), animal study (regular).
(b)

Pharmacodynamic interactions with CBZ
Antiepileptic efficacy of CBZSide effects related to CBZ
PotentiationInhibitionNo effectPotentiationReductionNo effect

Acorus calamus Linn.
Melatonin
CaffeineXiao-yao-san  
Melatonin  
Alcohol
Cassia auriculata Linn.
Cardiospermum halicacabum Linn.

Study type: human study (bold), animal study (regular).