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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 901943, 15 pages
Network-Based Biomarkers for Cold Coagulation Blood Stasis Syndrome and the Therapeutic Effects of Shaofu Zhuyu Decoction in Rats
1Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing 210046, China
2College of Pharmacy, State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300071, China
Received 25 May 2013; Accepted 1 August 2013
Academic Editor: Aiping Lu
Copyright © 2013 Shulan Su et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Figure S1: Figure S1 displays the TIC chromatography of the first, third, fifth, seventh, eighth day during animal model preparation.
Figure S2: Figure S2 showed the metabolic profiling changes during the eight days of animal model preparation.
Figure S3: Figure S3 displays the typical base peak intensity (BPI) chromatograms in positive and negative ion modes of plasma and urine samples collected from normal and model rats.
Figure S4: Figure S4 showed the summary of pathway analysis with MetPA in plasma and urine.