Bioactive Fraction of Geopropolis from Melipona scutellaris Decreases Neutrophils Migration in the Inflammatory Process: Involvement of Nitric Oxide Pathway
Figure 2
Inhibitory effect of the ethanolic extract of geopropolis (EEGP) and aqueous fraction (AF) on rolling (a) and adhesion (b) of leukocytes assessed by intravital microscopy in mesenteric tissue of mice, 2 and 4 h after IP injection of carrageenan 500 μg/cavity. Mice were pretreated with vehicle (saline and carrageenan), EEGP, or aqueous fraction (10 mg/kg). The data are expressed as mean ± SEM, . Symbols indicate statistical difference (, Tukey test). #Compared to the saline group; *compared to the carrageenan group.